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Acetyldiethylstilbestrol 2,3,4-Tri-o-Acetyl--D-Glucuronide Methyl Ester CAS NO 40269-22-5
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CAS No.:40269-22-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Acetyldiethylstilbestrol 2,3,4-Tri-o-Acetyl--D-Glucuronide Methyl Ester is a chemically modified derivative of diethylstilbestrol, designed for advanced research and synthesis applications. This high-purity intermediate is critical for scientists developing analytical standards, metabolic studies, and novel pharmaceutical compounds. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers requiring precise and reliable synthetic building blocks.
Application
- Pharmaceutical Research & Development: Serves as a key synthetic intermediate or reference standard in the development and study of hormone-related therapeutics and their metabolic pathways.
- Analytical Chemistry: Used as a high-purity calibration standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and High-Performance Liquid Chromatography (HPLC) for quantitative analysis in complex matrices.
- Metabolite Synthesis & Study: Essential for the synthesis and characterization of glucuronidated metabolites in pharmacokinetic and drug metabolism research.
- Biochemical Research: Employed in academic and industrial labs to investigate estrogen receptor interactions and the biochemical fate of synthetic estrogens.
- Fine Chemical Synthesis: Acts as a protected precursor for the further chemical modification and creation of novel derivatives with potential biological activity.
Basic Information
| Item | Details |
|---|---|
| Product Name | Acetyldiethylstilbestrol 2,3,4-Tri-o-Acetyl--D-Glucuronide Methyl Ester |
| CAS No. | 40269-22-5 |
| Molecular Formula | C34H38O12 |
| Molecular Weight | 638.66 g/mol |
| Synonyms | Diethylstilbestrol 2,3,4-Triacetylglucuronide Methyl Ester; DES Triacetylglucuronide Methyl Ester; 2,3,4-Tri-O-acetyl-α/β-D-glucopyranuronic acid methyl ester 1-[4,4'-(1,2-diethyl-1,2-ethenediyl)bis-phenoxy] derivative; Acetylated Diethylstilbestrol Glucuronide Methyl Ester; (E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)diphenyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronic acid methyl ester |
| EINECS | Contact for details |
Quality Control
Every batch of Acetyldiethylstilbestrol 2,3,4-Tri-o-Acetyl--D-Glucuronide Methyl Ester is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles is available for every lot upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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