Description

2'-Chloro-2'-Deoxyuridine 5'-Diphosphate is a modified nucleotide analog with significant biochemical and pharmaceutical research applications. This compound is valued for its role as a substrate or inhibitor in enzymatic studies, particularly those involving DNA polymerases and kinases. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in nucleoside metabolism research, antiviral drug discovery, and the synthesis of novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study DNA polymerase activity and nucleotide metabolism pathways.
• Antiviral Drug Development: Serves as a key intermediate or active component in the research and synthesis of novel nucleoside-based antiviral compounds.
• Molecular Biology: Employed in the study of DNA replication, repair mechanisms, and the effects of modified nucleotides on nucleic acid structure and function.
• Pharmaceutical Intermediates: Acts as a critical building block in the synthesis of more complex nucleotide analogs and prodrugs for therapeutic applications.
• Enzyme Kinetics: Utilized to investigate the kinetics and specificity of kinases and other phosphoryl-transfer enzymes.
• Diagnostic Reagent Development: Can be incorporated into diagnostic kits and assays for detecting specific enzymatic activities or biomarkers.

Basic Information

Product Name	2'-Chloro-2'-Deoxyuridine 5'-Diphosphate
CAS No.	40111-66-8
Molecular Formula	C9H13ClN2O11P2
Molecular Weight	438.61 g/mol
Synonyms	2'-Chloro-2'-deoxyuridine-5'-diphosphate; 5'-CDP-2'-Cl-dU; 2'-Chloro-dUDP; 2'-Cl-2'-dUDP; 2'-Chloro-2'-deoxyuridine diphosphate; 2'-Chloro-2'-deoxy-5'-uridine diphosphate; 5'-Diphosphoric acid 2'-chloro-2'-deoxyuridine ester; UDP analog, 2'-chloro
EINECS	Contact for details

Quality Control

Our 2'-Chloro-2'-Deoxyuridine 5'-Diphosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.