Description

Monoiodoamphenicol CAS NO 40027-73-4 is a halogenated derivative of chloramphenicol, serving as a key intermediate in the synthesis of novel antimicrobial agents and other fine chemicals. Its value lies in providing a versatile chemical scaffold for pharmaceutical research and development, enabling the exploration of structure-activity relationships. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and life science sectors for developing new therapeutic candidates and diagnostic tools.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antibiotic and antimicrobial compounds.
• Research & Development: Used in medicinal chemistry for studying structure-activity relationships (SAR) of chloramphenicol analogs.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and microbiological studies.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value chemical entities for various research applications.
• Veterinary Pharmaceutical Development: Potential use in the R&D of new antimicrobial treatments for veterinary applications.

Basic Information

Product Name	Monoiodoamphenicol
CAS No.	40027-73-4
Molecular Formula	C11H12Cl2INO5
Molecular Weight	452.03 g/mol
Synonyms	D(-)-threo-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-iodophenyl)ethyl]acetamide; 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-iodophenyl)propan-2-yl]acetamide; Iodamphenicol; Chloramphenicol Monoiodo Derivative; 4'-Iodochloramphenicol; 1-(4-Iodophenyl)-2-dichloroacetamido-1,3-propanediol; D-threo-4'-Iodochloramphenicol
EINECS	Contact for details

Quality Control

Our Monoiodoamphenicol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency for your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.