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2-Bromo-n-[(1R,2R)-2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide CAS NO 40027-72-3


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CAS No.:40027-72-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-n-[(1R,2R)-2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a critical building block for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly where specific stereochemistry is required for biological activity.
  • Organic Synthesis Building Block: Used in multi-step synthetic routes to create complex molecules for medicinal chemistry and chemical biology studies.
  • Asymmetric Catalyst Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic systems.
  • Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in laboratories.
  • Academic & Industrial R&D: Fundamental material for investigating new chemical reactions and pathways in university and corporate research settings.

Basic Information

Product Name 2-Bromo-n-[(1R,2R)-2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
CAS No. 40027-72-3
Molecular Formula C12H15BrN2O5
Molecular Weight 347.17 g/mol
Synonyms (1R,2R)-2-Acetamido-1-(bromoacetyl)-2-(4-nitrophenyl)ethane-1,2-diol; 2-Bromo-N-[(1R,2R)-1,2-dihydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; 2-Bromoacetamide derivative of (1R,2R)-2-Amino-1-(hydroxymethyl)-2-(4-nitrophenyl)ethane-1,2-diol; (1R,2R)-2-(2-Bromoacetamido)-2-(4-nitrophenyl)propane-1,3-diol; Bromoacetyl derivative of a chiral nitrophenyl ethanolamine
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Quality Control

Our 2-Bromo-n-[(1R,2R)-2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% de
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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