Description

Z-Ala-Gly-Nh2 is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of alanylglycine amide. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where its protecting group allows for selective deprotection and controlled chain elongation. It is primarily needed by pharmaceutical researchers, biotech companies, and fine chemical manufacturers engaged in the development and production of novel peptides for therapeutic and diagnostic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled assembly of longer, more complex peptide sequences.
• Pharmaceutical Research: Utilized in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Biochemical Research: Used as a substrate or standard in enzymatic studies and proteomics research.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Fine Chemical Production: Acts as a precursor for custom peptides and specialized amino acid derivatives.

Basic Information

Product Name	Z-Ala-Gly-Nh2
CAS No.	4976-59-4
Molecular Formula	C₁₃H₁₇N₃O₄
Molecular Weight	279.29 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-L-alanylglycinamide; Z-L-Ala-Gly-NH₂; Cbz-Ala-Gly-NH₂; N-Carbobenzoxy-L-alanylglycinamide; Benzyloxycarbonyl-L-alanylglycinamide; L-Alanine, N-[(phenylmethoxy)carbonyl]glycylamide; Z-A-G-NH2; CBZ-L-Ala-Gly-NH2
EINECS	225-618-5

Quality Control

Our Z-Ala-Gly-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.