Description

Benzene, 1,2,5-Trifluoro-3-Methoxy- is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the strategic trifluoro and methoxy substituents on the benzene ring. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, altering properties like chemical resistance, thermal stability, and surface energy.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille) to create complex biaryl structures common in many functional materials.
• Chemical Research: A valuable reagent in academic and industrial laboratories for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	Benzene, 1,2,5-Trifluoro-3-Methoxy-
CAS No.	4920-36-9
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	1,2,5-Trifluoro-3-methoxybenzene; 3-Methoxy-1,2,5-trifluorobenzene; 1,2,5-Trifluoro-3-methoxybenzene; 3-Methoxy-1,2,5-trifluorobenzene; 1,2,5-Trifluoro-3-methoxy-benzene; Benzene, 1,2,5-trifluoro-3-methoxy-; 4920-36-9
EINECS	Contact for details

Quality Control

Our Benzene, 1,2,5-Trifluoro-3-Methoxy- is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and scale-up applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.