Description

(2S)-2-Acetamido-4-Methoxy-4-Oxobutanoic Acid CAS NO 4910-43-4 is a high-purity chiral building block and protected amino acid derivative. This compound is of significant value in synthetic organic chemistry, particularly for the construction of complex peptides and biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the synthesis of fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected aspartic acid analog for the solid-phase and solution-phase synthesis of custom peptides.
• Bioconjugation Chemistry: Useful for creating labeled compounds or antibody-drug conjugates (ADCs) due to its reactive carboxylic acid and amide functionalities.
• Chemical Biology Research: Employed as a tool compound or precursor in studying enzyme mechanisms and protein interactions.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic Research: A valuable reagent for methodology development in asymmetric synthesis and organocatalysis.

Basic Information

Product Name	(2S)-2-Acetamido-4-Methoxy-4-Oxobutanoic Acid
CAS No.	4910-43-4
Molecular Formula	C7H11NO5
Molecular Weight	189.17 g/mol
Synonyms	N-Acetyl-L-aspartic acid β-methyl ester; L-Aspartic acid, N-acetyl-, 4-methyl ester; (S)-2-Acetamidosuccinic acid 4-methyl ester; N-Acetyl-4-O-methyl-L-aspartic acid; N-Acetyl-L-aspartic acid methyl ester; Methyl N-acetyl-L-aspartate; Ac-Asp-OMe; 4910-43-4
EINECS	Contact for details

Quality Control

Our (2S)-2-Acetamido-4-Methoxy-4-Oxobutanoic Acid is manufactured under a strict quality management system. We provide material typically meeting ≥98% purity (by HPLC), with specifications tailored for research and pharmaceutical intermediate use. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.