Description

5-(2-Chloroacetamido)-2,4,6-Triiodo-Isophthalic Acid is a high-purity iodinated aromatic compound, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in its precise molecular architecture, which is essential for producing high-contrast, non-ionic X-ray contrast media agents. This compound is primarily required by manufacturers in the pharmaceutical and fine chemical sectors, where consistent quality and reliable supply are paramount for downstream drug development and production.

Application

• Key Intermediate for X-Ray Contrast Media: A vital building block in the synthesis of modern, non-ionic iodinated contrast agents used in diagnostic imaging (CT scans, angiography).
• Pharmaceutical Research & Development: Used in the discovery and process development of new diagnostic pharmaceuticals.
• Fine Chemical Synthesis: Employed in specialized organic synthesis routes requiring a highly functionalized, tri-iodinated benzene core.
• Contrast Agent Manufacturing: Integral to the commercial-scale production chain of final formulated contrast media products.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control in contrast agent production.

Basic Information

Product Name	5-(2-Chloroacetamido)-2,4,6-Triiodo-Isophthalic Acid
CAS No.	4873-45-4
Molecular Formula	C11H6ClI3NO5
Molecular Weight	673.34 g/mol
Synonyms	2,4,6-Triiodo-5-[(2-chloroacetyl)amino]-1,3-benzenedicarboxylic Acid; 5-Acetamido-2,4,6-triiodoisophthalic Acid Chloride Derivative; Isophthalic Acid, 5-(2-chloroacetamido)-2,4,6-triiodo-; 5-(Chloroacetylamino)-2,4,6-triiodoisophthalic Acid; 2,4,6-Triiodo-5-(2-chloroacetamido)isophthalic Acid; Iodinated Isophthalic Acid Derivative; Contrast Media Intermediate; CAS 4873-45-4
EINECS	Contact for details

Quality Control

Our production of 5-(2-Chloroacetamido)-2,4,6-Triiodo-Isophthalic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.