Description

3-Hydroxy-3-Methylcyclobutanecarbonitrile is a versatile and synthetically valuable nitrile derivative featuring a functionalized cyclobutane ring. This compound matters as a crucial chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical development, and the synthesis of specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators due to its reactive nitrile and hydroxyl groups.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel polymers and specialty chemicals with tailored thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functional group transformation reactions.

Basic Information

Product Name	3-Hydroxy-3-Methylcyclobutanecarbonitrile
CAS No.	4844-51-3
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	3-Hydroxy-3-methylcyclobutanecarbonitrile; 3-Methyl-3-hydroxycyclobutanecarbonitrile; 3-Hydroxy-3-methyl-1-cyanocyclobutane; 1-Cyano-3-hydroxy-3-methylcyclobutane; (3-Hydroxy-3-methylcyclobutyl)methanenitrile; HMCCN
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-3-Methylcyclobutanecarbonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.