Description

Z-Phe-Nh2 is a protected amino acid derivative, specifically the benzyloxycarbonyl (Z or Cbz) protected form of phenylalanine amide. This compound is a crucial chiral building block and intermediate in the synthesis of peptides, peptidomimetics, and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Serves as a protected amino acid component in solid-phase and solution-phase peptide synthesis (SPPS).
• Biochemical Research: Used in academic and industrial R&D for studying enzyme-substrate interactions and designing novel bioactive compounds.
• Agrochemical Development: Employed as a building block for creating chiral active ingredients with specific biological activity.
• Fine Chemical Production: A versatile intermediate for synthesizing complex organic molecules requiring the phenylalanine amide moiety.

Basic Information

Item	Detail
Product Name	Z-Phe-Nh2
CAS No.	4801-80-3
Molecular Formula	C17H18N2O3
Molecular Weight	298.34 g/mol
Synonyms	N-Carbobenzoxy-L-phenylalaninamide; Cbz-L-Phenylalaninamide; Z-L-Phenylalaninamide; Nα-Cbz-L-phenylalaninamide; (S)-2-(((Benzyloxy)carbonyl)amino)-3-phenylpropanamide; Benzyl N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate; CBZ-PHE-NH2; Z-Phenylalanine amide
EINECS	Contact for details

Quality Control

Our Z-Phe-Nh2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.