Description

1-(8-Chloro-10,11-Dihydrodibenzo[B,F]Thiepin-10-Yl)-4-Methyl-Piperazine Maleate is a high-purity, synthetically derived organic compound that serves as a critical intermediate in advanced pharmaceutical research and development. Its value lies in its specific molecular architecture, which is essential for synthesizing novel therapeutic agents targeting central nervous system disorders. This compound is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new psychotropic medications and neuropharmacological studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel tricyclic antidepressant and antipsychotic drug candidates.
• Neuropharmacology Research: Used as a reference standard or active moiety in studies investigating serotonin and dopamine receptor modulation.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new chemical entities (NCEs).
• Biochemical Research: Utilized in vitro assays to study ligand-receptor interactions relevant to neurological pathways.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of more complex, target-specific molecules for clinical trials.

Basic Information

Product Name	1-(8-Chloro-10,11-Dihydrodibenzo[B,F]Thiepin-10-Yl)-4-Methyl-Piperazine Maleate
CAS No.	4789-68-8
Molecular Formula	C22H24ClN2O2S
Molecular Weight	423.96 g/mol
Synonyms	Perathiepin Maleate; 8-Chloro-10-(4-methyl-1-piperazinyl)-10,11-dihydrodibenzo[b,f]thiepin Maleate; 1-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine Maleate; Perathiepine Maleate; 4789-68-8; Peratiapine Maleate; 10-(4-Methyl-1-piperazinyl)-8-chloro-10,11-dihydrodibenzo[b,f]thiepin Maleate
EINECS	Contact for details

Quality Control

Our 1-(8-Chloro-10,11-Dihydrodibenzo[B,F]Thiepin-10-Yl)-4-Methyl-Piperazine Maleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.