Description

N,N,β-Trimethyl-10H-Phenothiazine-10-Propylamine 5,5-Dioxide Monohydrochloride is a high-purity, chemically defined phenothiazine derivative, a class of compounds known for their significant biological and chemical activity. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for use as a key synthetic intermediate or a reference standard.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel phenothiazine-based active pharmaceutical ingredients (APIs) with potential neurological or anti-infective applications.
• Chemical Research & Development: Used as a precursor or model compound in organic synthesis for developing new chemical entities and studying structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical and chemical analysis laboratories.
• Biochemical Research: Employed in life science research to investigate biological pathways, receptor binding, or enzyme inhibition where the phenothiazine core is relevant.
• Material Science Exploration: Investigated for potential use in the development of specialty materials, such as organic semiconductors or photostabilizers, due to its conjugated structure.

Basic Information

Product Name	N,N,β-Trimethyl-10H-Phenothiazine-10-Propylamine 5,5-Dioxide Monohydrochloride
CAS No.	4784-40-1
Molecular Formula	C₁₈H₂₃ClN₂O₂S
Molecular Weight	366.90 g/mol
Synonyms	Promethazine Sulfoxide Hydrochloride; Promethazine S-Oxide Hydrochloride; 10-[3-(Dimethylamino)propyl]-N,N,β-trimethyl-10H-phenothiazine-10-ethanamine 5,5-Dioxide Monohydrochloride; 1-(10H-Phenothiazin-10-yl)-N,N,β-trimethylpropan-1-amine 5,5-Dioxide Hydrochloride; N,N,β-Trimethyl-10H-phenothiazine-10-propanamine 5,5-Dioxide Hydrochloride; Promethazine Metabolite Sulfoxide HCl; Phenothiazine-10-propanamine derivative hydrochloride
EINECS	Contact for details

Quality Control

Our N,N,β-Trimethyl-10H-Phenothiazine-10-Propylamine 5,5-Dioxide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.