Description

Tris(2-Methoxyphenyl)Phosphine is a specialized organophosphorus ligand characterized by its sterically hindered and electron-rich methoxy-substituted aromatic rings. This compound matters as a highly effective ligand in transition metal catalysis, facilitating critical cross-coupling and other organometallic reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing complex molecules.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) for C-C bond formation.
• Utilized in asymmetric hydrogenation and other chiral catalysis when used with appropriate metal centers.
• Acts as a key precursor or intermediate in the synthesis of more complex phosphine ligands and organometallic complexes.
• Employed in academic and industrial research for developing new catalytic systems and methodologies.
• Finds use in the manufacture of OLED materials and electronic chemicals where precise molecular control is required.
• Applied in fine chemical and pharmaceutical intermediate synthesis, particularly for complex, sterically demanding substrates.

Basic Information

Product Name	Tris(2-Methoxyphenyl)Phosphine
CAS No.	4731-65-1
Molecular Formula	C21H21O3P
Molecular Weight	352.37 g/mol
Synonyms	Tris(o-methoxyphenyl)phosphine; Phosphorous Tris(2-methoxyphenyl) Ester; 2-Methoxyphenylphosphine, tris-; Tris(2-anisyl)phosphine; o-Methoxyphenylphosphine, tris-; P(2-MeOC6H4)3; Ligand for Cross-Coupling
EINECS	Contact for details

Quality Control

Our Tris(2-Methoxyphenyl)Phosphine is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). Due to its sensitivity to oxidation, minimize exposure to air during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.