Description

n-[(p-Methoxybenzyloxy)Carbonyl]Glycine is a specialized amino acid derivative featuring a p-methoxybenzyloxycarbonyl (PMB) protecting group. This compound is of significant value in organic synthesis, particularly in peptide chemistry, where it serves as a key building block for the controlled assembly of peptide chains. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex peptides, bioactive molecules, and novel therapeutic agents.

Application

• Peptide Synthesis Intermediate: A crucial building block in solid-phase and solution-phase peptide synthesis for introducing glycine residues with orthogonal protection.
• Pharmaceutical Research & Development: Used in the R&D of novel peptide-based drugs, prodrugs, and bioactive compounds.
• Bioconjugation Chemistry: Serves as a linker or spacer molecule in the conjugation of peptides to other biomolecules, polymers, or surfaces.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides and molecular probes for studying biological processes.
• Fine Chemical Synthesis: Acts as a protected glycine derivative in the multi-step synthesis of complex organic molecules and natural product analogs.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic and medicinal chemistry.

Basic Information

Product Name	n-[(p-Methoxybenzyloxy)Carbonyl]Glycine
CAS No.	4596-54-7
Molecular Formula	C11H13NO5
Molecular Weight	239.22 g/mol
Synonyms	PMB-Gly-OH; N-[(4-Methoxybenzyl)oxy]carbonylglycine; Glycine, N-[(4-methoxyphenyl)methoxy]carbonyl-; (p-Methoxybenzyloxycarbonyl)glycine; 4-Methoxybenzyloxycarbonyl-glycine; Z(OMe)-Gly-OH; NSC 334153; Fmoc-Gly-OH analog (protected)
EINECS	Contact for details

Quality Control

Our n-[(p-Methoxybenzyloxy)Carbonyl]Glycine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards expected in fine chemical and pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.