Description

Gitoxin CAS NO 4562-36-1 is a potent cardiac glycoside, a secondary metabolite derived from *Digitalis* species. This compound is of significant interest in pharmaceutical research and development due to its specific activity on the sodium-potassium ATPase pump, influencing myocardial contractility. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular drug discovery, biochemical studies, and as a reference standard for analytical purposes.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and method validation in drug analysis.
• Biochemical Research: Serves as a critical tool in studying the mechanism of cardiac glycosides, ion transport, and cell signaling pathways.
• Drug Discovery & Development: Acts as a lead compound or intermediate in the research and synthesis of novel cardiovascular therapeutics.
• Academic Research: Employed in university and institutional labs for pharmacological and toxicological studies.
• Analytical Chemistry: Functions as an internal or external standard in chromatographic (HPLC, LC-MS) assays for digitalis glycosides.

Basic Information

Product Name	Gitoxin
CAS No.	4562-36-1
Molecular Formula	C₄₁H₆₄O₁₄
Molecular Weight	780.94 g/mol
Synonyms	16-Formylgitoxin; Anhydrogitalin; Gitoxigenin 3-[O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranoside]; 3β-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14,16β-dihydroxy-19-oxo-5β-card-20(22)-enolide; Digitalis glycoside
EINECS	224-928-8

Quality Control

Our Gitoxin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.