Description

S(-)-n-(α-Hydroxymethylphenethyl)Benzamide is a chiral organic compound of significant interest in advanced chemical synthesis. This enantiomerically pure substance serves as a critical building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Employed as a precursor or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where biological activity is enantiomer-dependent.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chiral analysis (e.g., HPLC, SFC).

Basic Information

Product Name	S(-)-n-(α-Hydroxymethylphenethyl)Benzamide
CAS No.	4503-96-2
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	(S)-(-)-N-(α-Hydroxymethylphenethyl)benzamide; (S)-N-(1-Hydroxy-1-phenylpropan-2-yl)benzamide; (S)-2-Benzamido-1-phenylethanol; (S)-N-(1-Hydroxy-1-phenyl-2-propyl)benzamide; (-)-N-(α-Hydroxymethylphenethyl)benzamide; S-(-)-HPB; Benzamide, N-[(1S)-1-hydroxy-1-phenyl-2-propyl]-
EINECS	Contact for details

Quality Control

Our S(-)-n-(α-Hydroxymethylphenethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.