Description

Pyridoxal 5'-Diphospho-5'-Adenosine is a crucial coenzyme derivative, serving as the active form of vitamin B6 (pyridoxal phosphate) conjugated with adenosine diphosphate. This compound is essential for numerous enzymatic transamination and decarboxylation reactions in amino acid metabolism. It is primarily utilized in advanced biochemical research, pharmaceutical development, and as a critical reagent in enzymatic studies and diagnostic applications.

Application

• Biochemical Research: Essential cofactor for studying pyridoxal phosphate-dependent enzymes, including transaminases, decarboxylases, and racemases.
• Pharmaceutical Development: Used in the research and synthesis of novel therapeutics targeting metabolic pathways and neurological functions.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical assay kits for measuring specific enzyme activities in serum or tissue samples.
• Enzymology Studies: Critical for in vitro enzyme kinetics, mechanism of action studies, and enzyme reconstitution experiments.
• Nutraceutical & Cosmetic Research: Investigated for its role in cellular metabolism and potential applications in advanced skincare and wellness products.
• Academic & Industrial R&D: Serves as a high-purity standard and reference material in laboratories worldwide.

Basic Information

Product Name	Pyridoxal 5'-Diphospho-5'-Adenosine
CAS No.	4500-99-6
Molecular Formula	C17H23N6O14P2
Molecular Weight	621.35 g/mol
Synonyms	Pyridoxal Adenosine Diphosphate; PLP-ADP; Pyridoxal 5'-Phosphate Adenosine Diphosphate; Vitamin B6 Coenzyme Conjugate; Adenosine 5'-(trihydrogen diphosphate) P'→5'-ester with 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde; Coenzyme B6-ADP; 5'-O-{[(3-Hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl)methyl]hydroxyphosphoryl}adenosine
EINECS	Contact for details

Quality Control

Our Pyridoxal 5'-Diphospho-5'-Adenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or production standards. Custom purity grades and specific analytical data packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.