Description

(3-Hydroxy-4-Methoxy-Phenyl)-Acetonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both phenolic and methoxy substituents, makes it a valuable building block for constructing complex molecules with specific functionalities. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and advanced polymer modifiers.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating agents and organocatalysts.
• Academic and Industrial R&D: Employed in methodological research and scale-up studies for new synthetic pathways.
• Flavor and Fragrance Industry: Intermediate for the synthesis of certain aromatic compounds used in specialty formulations.

Basic Information

Product Name	(3-Hydroxy-4-Methoxy-Phenyl)-Acetonitrile
CAS No.	4468-58-0
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	4-Methoxy-3-hydroxybenzyl cyanide; 3-Hydroxy-4-methoxybenzyl cyanide; (4-Methoxy-3-hydroxyphenyl)acetonitrile; 2-(4-Methoxy-3-hydroxyphenyl)acetonitrile; Homovanillyl nitrile; Vanillylacetonitrile; 4468-58-0; (3-Hydroxy-4-methoxyphenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our (3-Hydroxy-4-Methoxy-Phenyl)-Acetonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.