Description

1,3-Dihydro-1,3-Dioxo-2H-Isoindole-2-Propanamide is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its unique isoindoline-1,3-dione (phthalimide) core structure makes it a versatile building block for the development of pharmaceuticals, agrochemicals, and specialty polymers. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and material science industries seeking to create novel molecules with specific functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the phthalimide pharmacophore.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the creation of high-performance polyimides and other specialty polymers with excellent thermal stability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and functional materials.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for metal catalysis and organocatalysis.

Basic Information

Product Name	1,3-Dihydro-1,3-Dioxo-2H-Isoindole-2-Propanamide
CAS No.	4443-33-8
Molecular Formula	C11H8N2O3
Molecular Weight	216.19 g/mol
Synonyms	2-(2-Carbamoylethyl)isoindoline-1,3-dione; N-(1,3-Dioxoisoindolin-2-yl)propionamide; Phthalimide-2-propionamide; 2-(1,3-Dioxoisoindolin-2-yl)propanamide; 3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanamide; 4443-33-8; Propanamide, 3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-1,3-Dioxo-2H-Isoindole-2-Propanamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.