Description

3β-Hydroxy-5β-Carda-8(14),20(22)-Dienolide CAS NO 4427-79-6 is a high-purity, specialized cardenolide derivative, a class of compounds known for their potent biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for research and development. It is essential for organizations in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise, high-quality building blocks for the synthesis of novel therapeutic agents or for analytical purposes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard in pharmacological studies to investigate sodium-potassium ATPase inhibition and related cardiac effects.
• Analytical Chemistry: Serves as a high-purity calibration standard for HPLC, LC-MS, and other chromatographic methods in quality control laboratories.
• Academic Research: Employed in universities and research institutes for studying the structure-activity relationships (SAR) of cardenolides.
• Fine Chemical Synthesis: A versatile building block for the preparation of more complex, functionalized steroidal molecules.

Basic Information

Product Name	3β-Hydroxy-5β-Carda-8(14),20(22)-Dienolide
CAS No.	4427-79-6
Molecular Formula	C₂₃H₃₂O₄
Molecular Weight	372.50 g/mol
Synonyms	3β-Hydroxy-5β-carda-8(14),20(22)-dienolide; 3β-Hydroxy-14,15-dinor-5β-card-8(14),20(22)-dienolide; 3β-Hydroxy-5β,14β-card-20(22)-enolide; 3-Epigitoxigenin; 3-Iso-gitoxigenin; 3-Epi-gitoxigenin; 3β-Hydroxy-5β-card-20(22)-enolide; Gitoxigenin, 3-epi-
EINECS	Contact for details

Quality Control

Our 3β-Hydroxy-5β-Carda-8(14),20(22)-Dienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.