Description

Cyclobutanecarbonitrile CAS NO 4426-11-3 is a versatile organic nitrile compound featuring a strained four-membered cyclobutane ring. This unique structure makes it a valuable and high-demand chemical intermediate for advanced synthesis in research and industrial chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained ring systems for biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclobutane moiety can influence potency and selectivity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic materials with tailored properties.
• Organic Synthesis Reagent: Employed in cycloaddition reactions, ring-opening polymerizations, and as a nitrile source for the preparation of amides, acids, and heterocycles.
• Fragrance and Flavor Chemistry: Utilized as an intermediate for creating unique aroma chemicals with complex, nuanced scent profiles.
• Academic and R&D Laboratories: A critical reagent for methodological development and exploratory chemistry in universities and corporate research centers.

Basic Information

Product Name	Cyclobutanecarbonitrile
CAS No.	4426-11-3
Molecular Formula	C5H7N
Molecular Weight	81.12 g/mol
Synonyms	Cyclobutanecarbonitrile; Cyclobutyl cyanide; Cyclobutanenitrile; 1-Cyanocyclobutane; Cyclobutanecarboxonitrile; Cyclobutanecarboxylic acid nitrile; NSC 9377
EINECS	224-600-4

Quality Control

Our Cyclobutanecarbonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and batch-to-batch consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4380 - 1.4420
Density (20°C)	0.930 - 0.950 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.