Description

Cyclobutylacetonitrile is a versatile organic nitrile compound featuring a cyclobutyl group, serving as a valuable intermediate in advanced organic synthesis. Its unique structure makes it a critical building block for constructing complex molecular frameworks, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where precise chemical functionality is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those containing cyclobutane rings for conformational restriction.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the nitrile group can be transformed into various functional groups like amides or carboxylic acids.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags used in biochemical research and diagnostics.
• Fine Chemical Production: Acts as a starting material for the manufacture of various specialty and performance chemicals.

Basic Information

Product Name	Cyclobutylacetonitrile
CAS No.	4426-03-3
Molecular Formula	C6H9N
Molecular Weight	95.14 g/mol
Synonyms	Cyclobutaneacetonitrile; 2-Cyclobutylacetonitrile; (Cyclobutyl)acetonitrile; Cyclobutylmethyl cyanide; Cyclobutanemethyl cyanide; 2-Cyclobutylethanenitrile; Cyclobutyl cyanomethyl
EINECS	Contact for details

Quality Control

Our Cyclobutylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.