Description

1H-Indole-3-Propiononitrile is a versatile indole derivative, a key nitrile-containing intermediate in advanced organic synthesis. Its value lies in providing a reactive cyanoethyl group attached to the indole core, enabling the construction of complex molecules for pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and plant growth regulators, leveraging the bioactivity of the indole scaffold.
• Fine Chemical Production: Acts as a precursor for dyes, pigments, and other specialty chemicals where the indole structure imparts specific optical or electronic properties.
• Biochemical Research: Employed in the study of tryptophan metabolism and the synthesis of analogs for probing biological systems and enzyme mechanisms.
• Material Science: Investigated as a monomer or additive for creating advanced polymers with unique thermal or conductive characteristics.

Basic Information

Product Name	1H-Indole-3-Propiononitrile
CAS No.	4414-76-0
Molecular Formula	C11H10N2
Molecular Weight	170.21 g/mol
Synonyms	3-(3-Indolyl)propionitrile; Indole-3-propiononitrile; 3-Indolepropionitrile; 3-(1H-Indol-3-yl)propanenitrile; β-(3-Indolyl)propionitrile; 1H-Indole-3-propanenitrile; (3-Indolyl)propionitrile; 4414-76-0
EINECS	224-567-5

Quality Control

Our 1H-Indole-3-Propiononitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.