Description

2-(1H-1,2,3-Triazol-1-Yl)Acetonitrile is a versatile heterocyclic nitrile building block, crucial for constructing complex molecular architectures in advanced organic synthesis. Its value lies in the unique reactivity of the triazole ring and the cyano group, enabling efficient derivatization and cycloaddition reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of triazole-containing drug candidates, including potential antivirals, antifungals, and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and plant growth regulators that incorporate the 1,2,3-triazole pharmacophore.
• Click Chemistry Reagent: Serves as a precursor for generating azide or alkyne derivatives, facilitating Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and material science.
• Ligand and Catalyst Development: Employed in the preparation of nitrogen-donor ligands for transition metal catalysis and coordination chemistry.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for creating functional polymers with tailored thermal or electronic properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	2-(1H-1,2,3-Triazol-1-Yl)Acetonitrile
CAS No.	4368-69-8
Molecular Formula	C4H4N4
Molecular Weight	108.10 g/mol
Synonyms	1H-1,2,3-Triazole-1-acetonitrile; (1H-1,2,3-Triazol-1-yl)acetonitrile; 1-(Cyanomethyl)-1H-1,2,3-triazole; 1H-1,2,3-Triazol-1-ylacetonitrile; 1-Cyanomethyl-1,2,3-triazole; 1-Triazolylacetonitrile; Acetonitrile, (1H-1,2,3-triazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 2-(1H-1,2,3-Triazol-1-Yl)Acetonitrile is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.