Description

Acetyl Coenzyme A, [Acetyl-1-14C] is a radiolabeled biochemical reagent where the acetyl group is specifically tagged with carbon-14 at the 1-position. This compound is essential for tracing the metabolic fate of acetyl groups in biochemical pathways, providing critical insights into cellular energy production and biosynthesis. It is primarily utilized by researchers and scientists in pharmaceutical R&D, metabolic studies, and academic biochemistry for conducting precise tracer experiments and enzymatic assays.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the citric acid cycle (Krebs cycle), fatty acid synthesis, and cholesterol biosynthesis.
• Enzyme Kinetics & Assays: Essential substrate for measuring the activity of key enzymes such as choline acetyltransferase, citrate synthase, and acetyltransferases.
• Pharmaceutical Research: Employed in drug discovery to investigate mechanisms of action related to metabolism and to identify potential metabolic inhibitors.
• Biochemical Synthesis Studies: Facilitates research on acetylation reactions, including protein acetylation and the synthesis of acetylcholine.
• In Vitro Diagnostic Development: Used in the development of diagnostic kits and assays for metabolic disorders.
• Academic & Institutional Research: A fundamental tool for universities and research institutes conducting advanced studies in biochemistry and molecular biology.

Basic Information

Product Name	Acetyl Coenzyme A, [Acetyl-1-14C]
CAS No.	4332-37-0
Molecular Formula	C23H38N7O17P3S
Molecular Weight	809.57 g/mol (unlabeled)
Synonyms	Acetyl-CoA, [1-14C]Acetyl-CoA; Acetyl Coenzyme A (carbon-14 labeled); Coenzyme A, S-acetate (14C-labeled); Acetyl-Coenzyme A, [acetyl-1-14C]; Acetyl-S-CoA; 14C-Acetyl-CoA; S-Acetylcoenzyme A; AceCoA
EINECS	Contact for details

Quality Control

Every batch of Acetyl Coenzyme A, [Acetyl-1-14C] is produced and analyzed under stringent quality protocols to ensure high specific activity, radiochemical purity, and chemical stability. Our quality system ensures compliance with relevant standards for research-grade biochemicals. A comprehensive Certificate of Analysis (COA), detailing specific activity, purity by HPLC, and analytical data, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at or below -20°C. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated at -70°C or lower. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 90%
Identification (IR / NMR)	Conforms to structure
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.