Description

4-Iodoacetamidosalicylic Acid is a specialized salicylic acid derivative functionalized with an iodoacetamide group, making it a valuable bifunctional reagent. This compound is primarily utilized as a key intermediate in the synthesis of more complex molecules and as a biochemical tool for protein modification and labeling studies. It is of significant interest to researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing targeted therapies and diagnostic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Bioconjugation Reagent: Used for site-specific protein labeling and modification via its reactive iodoacetamide group, which targets cysteine residues.
• Proteomics Research: Employed in the development of activity-based probes (ABPs) to study enzyme function and mechanism in complex biological systems.
• Chemical Biology Tool: Facilitates the study of protein-protein interactions and the construction of antibody-drug conjugates (ADCs).
• Agrochemical Synthesis: Serves as an intermediate in the research and development of new crop protection agents with specific modes of action.
• Material Science: Potential use in creating functionalized polymers or surfaces for biosensor applications.

Basic Information

Product Name	4-Iodoacetamidosalicylic Acid
CAS No.	4323-00-6
Molecular Formula	C9H8INO4
Molecular Weight	321.07 g/mol
Synonyms	5-Amino-2-hydroxybenzoic Acid N-(Iodoacetyl); 4-(Iodoacetamido)salicylic Acid; N-Iodoacetyl-5-aminosalicylic Acid; 5-(Iodoacetamido)-2-hydroxybenzoic Acid; 4-Iodoacetamido-2-hydroxybenzoic Acid; Iodoacetamidosalicylic Acid; IASA; 4-IA-SA
EINECS	Contact for details

Quality Control

Our 4-Iodoacetamidosalicylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.