Description

4-(Trifluoromethoxy)Phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is prized for its ability to introduce the metabolically stable and lipophilic trifluoromethoxy group into target molecules, significantly altering their physicochemical properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients with enhanced performance.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory, antiviral, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group improves biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and unique surface properties.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound libraries.
• Fluorinated Dye & Pigment Intermediate: Used in the synthesis of specialty dyes and pigments with improved lightfastness and color properties.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenylacetic Acid
CAS No.	4315-07-5
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2-[4-(Trifluoromethoxy)phenyl]acetic Acid; p-(Trifluoromethoxy)phenylacetic Acid; 4-(Trifluoromethoxy)benzeneacetic Acid; α-(4-Trifluoromethoxyphenyl)acetic Acid; (4-Trifluoromethoxyphenyl)acetic Acid; OCF3-PAA; 4315-07-5; 4-(Trifluoromethoxy)benzenacetic Acid
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.