Description

3',4'-Dimethoxyphenyl Acetylene is a high-purity, versatile alkyne intermediate featuring a dimethoxy-substituted aromatic ring. This compound matters for its role as a critical building block in modern synthetic chemistry, enabling the construction of complex molecules through cross-coupling and cycloaddition reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in constructing novel fungicides, herbicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Serves as a monomer or cross-linker in the development of conductive polymers, liquid crystals, and organic semiconductors.
• Chemical Biology & Proteomics: Employed in click chemistry applications, such as CuAAC (Copper-Catalyzed Azide-Alkyne Cycloaddition), for bioconjugation and labeling.
• Organic Synthesis: A versatile reagent for Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form extended conjugated systems.
• Academic & Industrial R&D: Fundamental research tool in methodology development and exploring new reaction pathways in synthetic organic chemistry.

Basic Information

Product Name	3',4'-Dimethoxyphenyl Acetylene
CAS No.	4302-52-7
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	1-Ethynyl-3,4-dimethoxybenzene; 3,4-Dimethoxyphenylacetylene; (3,4-Dimethoxyphenyl)ethyne; 3,4-Dimethoxybenzeneacetylene; 3,4-Dimethoxy-1-ethynylbenzene; 3,4-Dimethoxyphenylethyne; 3,4-DMPA
EINECS	224-337-5

Quality Control

Our 3',4'-Dimethoxyphenyl Acetylene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.