Description

12-(Cbz-Amino)Dodecanoic Acid is a versatile, protected amino acid derivative featuring a dodecanoic acid backbone with a Cbz (carbobenzyloxy) protected amine group. This molecular architecture makes it a crucial building block for the synthesis of peptides, fatty acid conjugates, and other bioactive molecules where controlled amine functionality is required. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity intermediates for complex organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drugs, prodrugs, and lipid-conjugated therapeutics.
• Bioconjugation Chemistry: Used to introduce long-chain fatty acid spacers with protected amine handles onto proteins, antibodies, or other biomolecules.
• Peptide Synthesis (SPPS & Solution Phase): Serves as a protected amino acid component for constructing specialized peptide sequences with lipophilic character.
• Lipidomics Research: A valuable standard or synthetic precursor in the study of modified fatty acids and amino acid-lipid hybrids.
• Polymer & Material Science: Monomer for creating functionalized polymers with amine groups, useful in drug delivery systems and smart materials.
• Chemical Biology Probes: Synthesis of activity-based probes or affinity labels that incorporate a long, hydrophobic linker.

Basic Information

Product Name	12-(Cbz-Amino)Dodecanoic Acid
CAS No.	4272-07-5
Molecular Formula	C20H31NO4
Molecular Weight	349.47 g/mol
Synonyms	12-[(Benzyloxycarbonyl)amino]dodecanoic Acid; N-Cbz-12-Aminododecanoic Acid; N-[(Benzyloxy)carbonyl]-12-aminododecanoic Acid; 12-Aminododecanoic Acid N-Carbobenzoxy Derivative; N-Z-12-Aminolauric Acid; Z-12-Aminododecanoic Acid; (12-(((Benzyloxy)carbonyl)amino)dodecanoic acid); Lauric Acid, 12-amino-, N-carbobenzoxy-
EINECS	Contact for details

Quality Control

Our 12-(Cbz-Amino)Dodecanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.