Description

Naphthol As-Tr Phosphate, Monosodium Salt is a specialized organic phosphate ester salt primarily used as a chromogenic substrate in enzymatic assays. This compound matters for its high sensitivity and specificity in detecting alkaline phosphatase activity, a critical diagnostic and research tool. It is needed by manufacturers and research laboratories in the in-vitro diagnostics (IVD), life science research, and biochemical reagent sectors.

Application

• Primary Substrate in Diagnostic Kits: Key component in ELISA, immunoblotting, and histochemical staining kits for detecting alkaline phosphatase-labeled antibodies.
• Biochemical Research: Used in enzymatic activity assays and kinetic studies for phosphatase enzymes in academic and pharmaceutical research.
• Cell and Tissue Staining: Employed in histology and cytology for visualizing specific antigens or genetic material in situ.
• Molecular Biology: Utilized as a detection reagent in nucleic acid hybridization techniques like Southern and Northern blotting.
• Quality Control Reagent: Serves as a standard or control material in the production and validation of diagnostic assays.
• Pharmaceutical Testing: Applied in drug discovery and development for high-throughput screening assays targeting phosphatase pathways.

Basic Information

Item	Details
Product Name	Naphthol As-Tr Phosphate, Monosodium Salt
CAS No.	4264-93-1
Molecular Formula	C23H16NO6PNa
Molecular Weight	456.34 g/mol
Synonyms	Naphthol AS-TR Phosphoric Acid Sodium Salt; 3-Hydroxy-2-naphthoic acid 2,4-dimethylanilide phosphate monosodium salt; Sodium 3-[(2,4-dimethylphenyl)carbamoyl]-2-naphthyl phosphate; Naphthol AS-TR phosphate sodium salt; Fast Red TR Salt substrate; Alkaline Phosphatase Substrate; AS-TR phosphate; AS TR-PO4 Na
EINECS	Contact for details

Quality Control

Our Naphthol As-Tr Phosphate, Monosodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, spectral identification (IR/UV), and residual solvent analysis, to ensure it meets the stringent requirements for diagnostic and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Clear, colorless solution in water or buffer
Functional Performance	Suitable for use as an alkaline phosphatase substrate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.