Description

n-(5'-Phosphoribosyl)Anthranilate is a key biochemical intermediate in the biosynthesis of tryptophan and other indole derivatives. This compound matters for its critical role in enzymatic research and as a precursor in the study of metabolic pathways. It is primarily needed by research institutions, pharmaceutical developers, and biotechnology companies engaged in enzymology, metabolic engineering, and the synthesis of complex natural products. High-purity grades are essential for reproducible experimental results and process development.

Application

• Enzymology Research: Used as a substrate or intermediate in studies of anthranilate phosphoribosyltransferase and other enzymes in the tryptophan biosynthesis pathway.
• Metabolic Pathway Analysis: A critical reagent for investigating and modulating the shikimate and aromatic amino acid biosynthesis pathways in microorganisms and plants.
• Pharmaceutical Development: Serves as a building block or reference standard in the research and development of novel therapeutics targeting metabolic disorders.
• Biocatalyst and Fermentation Studies: Employed in microbial fermentation process optimization and in the development of biocatalytic routes for fine chemical synthesis.
• Biochemical Assay Standard: Used as a high-purity calibration standard in analytical methods such as HPLC or LC-MS for quantifying pathway metabolites.
• Academic Research & Teaching: A valuable tool for university laboratories teaching advanced biochemistry and molecular biology concepts.

Basic Information

Product Name	n-(5'-Phosphoribosyl)Anthranilate
CAS No.	4220-99-9
Molecular Formula	C12H15NO8P
Molecular Weight	332.22 g/mol
Synonyms	PRA; N-(5-Phospho-D-ribosyl)anthranilate; 5'-Phosphoribosylanthranilate; Anthranilic acid 5-phosphoribosyl ester; 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate; (2-{[(5-O-Phosphono-β-D-ribofuranosyl)amino]carbonyl}phenyl)acetate
EINECS	Contact for details

Quality Control

Our n-(5'-Phosphoribosyl)Anthranilate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC purity analysis and spectroscopic identification. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.