Description

4-tert-Butylbenzonitrile is a versatile aromatic nitrile derivative characterized by its tert-butyl substituent, which imparts unique steric and electronic properties. This compound serves as a critical high-purity intermediate in the synthesis of advanced materials and fine chemicals, where its benzonitrile core and bulky alkyl group are essential for constructing complex molecular architectures. It is primarily utilized by pharmaceutical research and agrochemical development teams, as well as by manufacturers of liquid crystals and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a sterically hindered benzonitrile moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the tert-butyl group enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of nematic and smectic liquid crystals for display technologies.
• Polymer Modification: Acts as a monomer or cross-linking agent in the production of high-performance engineering plastics and resins.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and cyano group transformations.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial R&D for exploring new organic reactions and material properties.

Basic Information

Product Name	4-tert-Butylbenzonitrile
CAS No.	4210-32-6
Molecular Formula	C11H13N
Molecular Weight	159.23 g/mol
Synonyms	p-tert-Butylbenzonitrile; 4-(1,1-Dimethylethyl)benzonitrile; 4-tert-Butylphenyl cyanide; Benzonitrile, 4-(1,1-dimethylethyl)-; 1-Cyano-4-tert-butylbenzene; p-t-Butylbenzonitrile; 4-(tert-Butyl)benzonitrile
EINECS	224-138-5

Quality Control

Our 4-tert-Butylbenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure a typical purity of ≥98.0% and conformity to agreed specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.