Description

2-Chlorobutyronitrile is a versatile halogenated nitrile intermediate with significant utility in advanced organic synthesis. Its reactive chloronitrile moiety makes it a valuable building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for chemists and process engineers in the fine chemical, pharmaceutical, and material science industries seeking to introduce functionalized butyronitrile units.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyanoalkyl or chlorinated side chains.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides where the chloronitrile group acts as a reactive handle.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and cyanoalkylation reactions to create more complex organic structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and resins.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and synthesizing novel heterocyclic compounds in R&D laboratories.

Basic Information

Product Name	2-Chlorobutyronitrile
CAS No.	4158-37-6
Molecular Formula	C₄H₆ClN
Molecular Weight	103.55 g/mol
Synonyms	Butyronitrile, 2-chloro-; 2-Chlorobutanenitrile; α-Chlorobutyronitrile; NSC 9375; 2-Chloro-1-cyanopropane; (RS)-2-Chlorobutyronitrile; (±)-2-Chlorobutyronitrile
EINECS	223-989-8

Quality Control

Our 2-Chlorobutyronitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, physical properties, and safety data are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.435 - 1.445
Density (20°C)	1.05 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.