Description

1,2-Bis(Di-tert-Butylphosphino)Ethane is a highly specialized, air-sensitive organophosphorus ligand widely used in homogeneous catalysis. Its primary value lies in its exceptional electron-donating and steric bulk, which significantly enhances the activity and selectivity of transition metal catalysts. This compound is essential for researchers and manufacturers in the pharmaceutical, fine chemical, and advanced materials sectors, particularly for cross-coupling reactions and asymmetric synthesis.

Application

• Homogeneous Catalysis: As a key ligand for palladium, nickel, and other transition metals in cross-coupling reactions (e.g., Suzuki, Heck, Negishi).
• Pharmaceutical Intermediates: Enabling the synthesis of complex, high-value drug molecules through selective C-C and C-X bond formation.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, agrochemicals, and performance materials requiring precise catalytic control.
• Asymmetric Hydrogenation: Employed in chiral ligand systems for the enantioselective reduction of prochiral substrates.
• Polymerization Catalysis: Acting as a co-catalyst or ligand in olefin polymerization and other polymer-forming processes.
• Academic & Industrial R&D: A critical reagent for developing new catalytic methodologies and optimizing existing synthetic routes.

Basic Information

Item	Details
Product Name	1,2-Bis(Di-tert-Butylphosphino)Ethane
CAS No.	4141-59-7
Molecular Formula	C18H40P2
Molecular Weight	318.46 g/mol
Synonyms	DTBPE; 1,2-Ethanediylbis[bis(1,1-dimethylethyl)phosphine]; Bis(di-tert-butylphosphino)ethane; Di-tert-butylphosphinoethane ligand; Ethylenebis(di-tert-butylphosphine); 1,2-Bis(di-tert-butylphosphanyl)ethane; DtBPE Ligand; (t-Bu)2PCH2CH2P(t-Bu)2
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Di-tert-Butylphosphino)Ethane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR (1H, 31P), HPLC, and elemental analysis, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom purity specifications for advanced research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Handle and dispense only in a controlled, oxygen-free environment (glove box or under Schlenk line conditions).

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.