Description

4,4'-Bis(Diphenylphosphanyl)-1,1'-Biphenyl is a high-value, bidentate phosphine ligand widely recognized for its role in facilitating transition metal-catalyzed reactions. This compound matters because it provides exceptional stability and electron-donating properties to metal centers, enabling more efficient and selective catalytic processes. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as cross-coupling, hydrogenation, and hydroformylation.

Application

• As a crucial ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi) for C-C bond formation in complex molecule synthesis.
• Employed in asymmetric hydrogenation and other chiral transformations for the production of enantiomerically pure pharmaceutical intermediates.
• Used in hydroformylation and hydrocyanation processes within industrial fine chemical manufacturing.
• Acts as a key component in catalyst systems for polymer synthesis and olefin polymerization.
• Facilitates C-H activation and functionalization reactions in modern synthetic methodology development.
• Serves as a precursor or modifier for creating specialized heterogeneous catalysts and catalytic surfaces.

Basic Information

Product Name	4,4'-Bis(Diphenylphosphanyl)-1,1'-Biphenyl
CAS No.	4129-44-6
Molecular Formula	C36H28P2
Molecular Weight	522.55 g/mol
Synonyms	BISBI; 4,4'-Bis(diphenylphosphino)biphenyl; 1,1'-Biphenyl, 4,4'-bis(diphenylphosphino)-; DIPHOS; 4,4'-Bis(diphenylphosphanyl)biphenyl; NSC 168088; BIS-BIPHENYLPHOSPHINE LIGAND; (4-(DIPHENYLPHOSPHINO)PHENYL)-DIPHENYLPHOSPHINE
EINECS	223-933-7

Quality Control

Our production of 4,4'-Bis(Diphenylphosphanyl)-1,1'-Biphenyl adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We maintain rigorous quality testing aligned with industry best practices, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	285 - 295 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.