Description

Lithium Dicyclohexylamide is a highly reactive, non-nucleophilic strong base widely used in organic synthesis. Its value lies in its ability to deprotonate a broad range of substrates with low nucleophilicity, minimizing unwanted side reactions. This makes it an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for the generation of enolates and other carbanions under mild conditions.

Application

• As a strong, non-nucleophilic base for the generation of kinetic enolates from carbonyl compounds.
• Deprotonation of weak carbon acids in the synthesis of complex natural products and active pharmaceutical ingredients (APIs).
• Lithiation reactions in the preparation of organolithium intermediates for cross-coupling and functionalization.
• Use in polymerization initiator systems and as a catalyst component for specialized polymer synthesis.
• Facilitating asymmetric synthesis and other stereoselective transformations in fine chemical production.
• Research and development of novel organic compounds in academic and industrial laboratories.

Basic Information

Product Name	Lithium Dicyclohexylamide
CAS No.	4111-55-1
Molecular Formula	C12H22LiN
Molecular Weight	187.24 g/mol
Synonyms	Lithium Bis(cyclohexyl)amide; Dicyclohexylamidolithium; Lithium Dicyclohexylamine; LDA (common abbreviation); Lithium Dicyclohexylazanide; N-Lithiodicyclohexylamine; Dicyclohexylamine, lithium salt; N-Cyclohexylcyclohexanamine lithium derivative
EINECS	Contact for details

Quality Control

Our Lithium Dicyclohexylamide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee the material meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Purity (HPLC)	Contact for details
Moisture (KF)	≤ 1.0%
Solvent Content (GC)	As specified (for solutions)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.