Description

2-Hydroxy-2-Methylbutanenitrile is a versatile organic nitrile compound featuring both hydroxyl and nitrile functional groups, making it a valuable chiral building block and intermediate in fine chemical synthesis. Its molecular structure is critical for introducing specific functionalities into target molecules, enabling the production of high-value pharmaceuticals and agrochemicals. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its nitrile and alcohol groups facilitate the construction of complex molecular architectures.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other specialty chemicals that benefit from its reactive functional groups.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel compound libraries.

Basic Information

Product Name	2-Hydroxy-2-Methylbutanenitrile
CAS No.	4111-08-4
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	2-Methyl-2-hydroxybutyronitrile; 2-Hydroxy-2-methylbutyronitrile; α-Hydroxyisovaleronitrile; 2-Methylbutyronitrile-2-ol; Acetone cyanohydrin, methyl-; (RS)-2-Hydroxy-2-methylbutyronitrile; 2-Methyl-2-hydroxybutanenitrile
EINECS	223-900-8

Quality Control

Our 2-Hydroxy-2-Methylbutanenitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and chiral purity assessment, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and specific physical parameters are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to the presence of functional groups that may be moisture-sensitive, containers should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Specific Impurities (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.