Description

Ac-Lys (Ac)-Oh CAS NO 499-86-5 is a chemically modified amino acid derivative, specifically Nε-Acetyl-L-lysine. This compound is a crucial building block in peptide synthesis and biochemical research, offering a protected lysine side chain that is essential for creating complex molecular architectures. It is primarily utilized by pharmaceutical researchers, peptide chemists, and biotechnology companies engaged in the development of novel therapeutics, diagnostic agents, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the controlled incorporation of lysine residues into peptide chains.
• Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in enzymatic studies, protein engineering, and as a substrate or standard in analytical methodologies.
• Proteomics and Biomarker Discovery: Employed in the synthesis of reference peptides and isotopic labels for mass spectrometry.
• Cosmetic Peptides: A component in the design and production of bioactive peptides for skincare and cosmetic applications.
• Antibody-Drug Conjugate (ADC) Development: Utilized in linker-payload synthesis for site-specific conjugation strategies.

Basic Information

Product Name	Ac-Lys (Ac)-Oh CAS NO 499-86-5
CAS No.	499-86-5
Molecular Formula	C8H16N2O3
Molecular Weight	188.22 g/mol
Synonyms	Nε-Acetyl-L-lysine; N6-Acetyl-L-lysine; Ac-Lys-OH; (S)-2-Amino-6-acetamidohexanoic acid; N-α-Acetyl-N-ε-acetyl-L-lysine; Acetyllysine; L-Lysine, N6-acetyl-; H-Ac-Lys-OH; N-Acetyl-L-lysine
EINECS	207-892-5

Quality Control

Our Ac-Lys (Ac)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support compliance with cGMP, ICH Q7, and REACH regulations as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+18.0° to +22.0° (c=1 in H2O)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.