Description

(2R,3R,4S,5R,6S)-3,4,5-Trihydroxy-2-(Hydroxymethyl)-6-(C-Methyl-n-Sulf Onatooxy-Carbonimidoyl)Sulfanyl-Oxane is a high-purity, specialized monosaccharide derivative with a sulfonated carbonimidoyl thioether functional group. This unique structure makes it a valuable chiral building block and intermediate for advanced synthetic chemistry, particularly in the development of novel bioactive compounds. It is essential for research and production in the pharmaceutical and fine chemical sectors, where precise stereochemistry and functional group manipulation are critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, especially nucleoside analogs and glycosidase inhibitors.
• Bioconjugation & Probe Development: Used in the design of chemical probes and affinity labels for studying enzyme mechanisms and protein interactions due to its reactive thioether and sulfonate groups.
• Glycochemistry Research: Acts as a modified sugar substrate for studying carbohydrate-processing enzymes or for creating non-natural glycoconjugates.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric catalysis, leveraging its multiple stereocenters.
• Material Science Precursor: Potential use in creating functionalized surfaces or polymers with specific sugar-based recognition properties.

Basic Information

Product Name	(2R,3R,4S,5R,6S)-3,4,5-Trihydroxy-2-(Hydroxymethyl)-6-(C-Methyl-n-Sulf Onatooxy-Carbonimidoyl)Sulfanyl-Oxane
CAS No.	497-77-8
Molecular Formula	C8H15NO10S2
Molecular Weight	349.33 g/mol
Synonyms	6-Deoxy-6-[[(methylsulfonyl)oxy]carbonimidoyl]thio]-D-glucopyranose; D-Glucose, 6-deoxy-6-[[(methylsulfonyl)oxy]carbonimidoyl]thio]-; 6-S-[(N-(Methylsulfonyloxy)carboximidoyl]-6-thio-D-glucose; Methyl sulfonatooxycarbonimidoyl 6-thio-β-D-glucopyranoside; 497-77-8; (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-[(methylsulfonyloxy)carbonimidoyl]sulfanyl]oxane-3,4,5-triol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for research and cGMP manufacturing environments. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to confirm identity, stereochemical purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and residual solvent levels is provided with each shipment to ensure traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.