Description

2-Fluoro-6-Nitroanisole is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic positioning of its functional groups, enabling selective derivatization for the creation of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aniline or benzimidazole motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments, where the nitro and methoxy groups facilitate chromophore development.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl and heteroaryl structures.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Fluoro-6-Nitroanisole
CAS No.	484-94-6
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	1-Fluoro-2-Methoxy-3-Nitrobenzene; 2-Methoxy-1-Fluoro-3-Nitrobenzene; 3-Nitro-2-Fluoroanisole; 2-Fluoro-3-Nitroanisole; 2-Fluoro-6-Nitrophenyl Methyl Ether; 6-Fluoro-2-Nitroanisole; o-Fluoro-m-nitroanisole
EINECS	207-610-9

Quality Control

Our 2-Fluoro-6-Nitroanisole is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and traceable to the production lot. We are committed to meeting the stringent requirements of cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.