Description

5-β-Pregnan-3-Alpha, 16-α-Diol-20-One is a high-purity steroid intermediate with the CAS registry number 481-10-7. This compound serves as a critical building block in the synthesis of more complex steroid-based pharmaceuticals and research chemicals. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of hormonal therapies and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of steroidal drugs and hormones.
• Research & Development: Used in biochemical and pharmacological research to study steroid metabolism, receptor interactions, and to develop new therapeutic agents.
• Reference Standard: Serves as a certified reference material (CRM) or analytical standard for quality control and method validation in laboratories.
• Fine Chemical Synthesis: Employed in organic synthesis for the preparation of novel steroid derivatives with potential biological activity.

Basic Information

Product Name	5-β-Pregnan-3-Alpha, 16-α-Diol-20-One
CAS No.	481-10-7
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	16α-Hydroxy-5β-pregnan-3α-ol-20-one; 3α,16α-Dihydroxy-5β-pregnan-20-one; 5β-Pregnane-3α,16α-diol-20-one; Allopregnan-3α,16α-diol-20-one; 16α-Hydroxyallopregnan-3α-ol-20-one
EINECS	207-566-3

Quality Control

Our 5-β-Pregnan-3-Alpha, 16-α-Diol-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.