Description

Phyllodulcin CAS NO 480-46-6 is a naturally occurring dihydroisocoumarin sweetener and flavor modifier. This compound is valued for its intense sweetness, which is several hundred times that of sucrose, and its unique ability to modify and enhance flavor profiles. It is a critical ingredient for manufacturers in the food, beverage, and nutraceutical industries seeking natural, high-potency sweetening solutions. Its role extends into research applications within organic chemistry and sensory science.

Application

• Natural High-Intensity Sweetener: Used in sugar-free and reduced-calorie food and beverage formulations.
• Flavor Modifier & Enhancer: Modifies bitter or metallic aftertastes and enhances overall flavor perception in functional drinks and dietary supplements.
• Nutraceutical & Dietary Supplement Ingredient: Incorporated into health supplements and vitamins where sugar content must be minimized.
• Pharmaceutical Syrup & Lozenge Formulation: Provides palatability in medicinal preparations without adding carbohydrates.
• Organic Synthesis Intermediate: Serves as a building block or reference standard in the synthesis of related sweeteners and dihydroisocoumarin derivatives.
• Sensory & Taste Research: Used as a standard compound in studies of sweet taste receptors and flavor interaction mechanisms.

Basic Information

Product Name	Phyllodulcin
CAS No.	480-46-6
Molecular Formula	C16H14O6
Molecular Weight	302.28 g/mol
Synonyms	3,4-Dihydro-8-hydroxy-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one; 8-Hydroxy-3-(4-hydroxyphenyl)-3,4-dihydro-1H-isochromen-1-one; Hydrangeol; Sweetener from Hydrangea macrophylla; Amacha sweetener
EINECS	207-555-7

Quality Control

Our Phyllodulcin is produced and tested under a strict quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for food, nutraceutical, and research applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications can be aligned with FCC and other relevant food-grade guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Optical Rotation	Contact for details
Solubility	Soluble in ethanol, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.