Description

n-[(3A,5B)-3-Hydroxy-24-Oxocholan-24-Yl]-(9Ci) Glycine is a high-purity conjugated bile acid derivative, specifically a glycine conjugate of a hydroxylated oxo-bile acid. This compound is critical for research and development in pharmaceutical chemistry, serving as a key intermediate or reference standard. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic pathway studies, drug discovery, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex steroid-based pharmaceuticals and bioactive molecules.
• Biochemical Research: Used as a reference standard or reagent in studies of bile acid metabolism, liver function, and digestive processes.
• Drug Discovery & Development: Acts as a precursor or a model compound for developing new therapeutics targeting metabolic disorders, liver diseases, or cholesterol regulation.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for the qualitative and quantitative analysis of bile acids and their conjugates in biological samples.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental research in steroid chemistry and endocrinology.

Basic Information

Product Name	n-[(3A,5B)-3-Hydroxy-24-Oxocholan-24-Yl]-(9Ci) Glycine
CAS No.	474-74-8
Molecular Formula	C₂₆H₄₁NO₅
Molecular Weight	447.61 g/mol
Synonyms	Glyco-3α-hydroxy-24-oxo-5β-cholanate; 3α-Hydroxy-24-oxo-5β-cholan-24-ylglycine; N-(3α-Hydroxy-24-oxo-5β-cholan-24-yl)glycine; 24-Oxo-3α-hydroxy-5β-cholanoylglycine; Glycine conjugate of 3α-hydroxy-24-oxo-5β-cholanic acid; (9CI) reference name; 474-74-8 (CAS Registry)
EINECS	Contact for details

Quality Control

Our n-[(3A,5B)-3-Hydroxy-24-Oxocholan-24-Yl]-(9Ci) Glycine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.