Description

13-cis-Retinal is a vital isomer of retinal, a key chromophore in the visual cycle. This compound is essential for research into the molecular mechanisms of vision, phototransduction, and the biochemistry of vitamin A derivatives. It serves as a critical intermediate and reference standard for pharmaceutical development, nutritional science, and advanced biochemical studies. Industries requiring high-purity biochemical precursors for research and development rely on this specific isomer for its defined biological activity.

Application

• Biochemical Research: A fundamental reagent for studying the visual cycle, rhodopsin regeneration, and photoisomerization processes.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and assay development of retinoid-based drugs and supplements.
• Nutraceutical Development: Acts as a key intermediate in the research and synthesis of advanced vitamin A formulations and pro-vitamin compounds.
• Cell Biology & Signaling Studies: Employed in investigations of retinoid signaling pathways, cellular differentiation, and gene expression regulation.
• Cosmeceutical Research: Used in studies exploring the effects of retinoids on skin cell biology for potential anti-aging and dermatological applications.

Basic Information

Product Name	13-cis-Retinal
CAS No.	472-86-6
Molecular Formula	C₂₀H₂₈O
Molecular Weight	284.44 g/mol
Synonyms	13-Z-Retinal; (13Z)-Retinal; neo-b-Retinal; iso-Retinal a; 13-cis-Retinaldehyde; 13-cis-Vitamin A aldehyde; all-trans-Retinal (isomer); Retinene (isomer)
EINECS	207-457-0

Quality Control

Our 13-cis-Retinal is manufactured and tested under strict quality management systems. Each batch is analyzed to ensure high chemical purity and isomer specificity, with testing typically including identification by spectroscopic methods and purity assay by HPLC. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Isomeric Purity (13-cis)	≥ 90.0% (by HPLC)
Solubility	Soluble in ethanol, DMSO, chloroform; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.