Description

Lupulone is a key prenylated acylphloroglucinol compound, a principal component of hop resins (beta acids) known for its distinct chemical structure and biological activity. This compound matters significantly for its role as a natural preservative and bioactive agent, offering inherent antimicrobial and antioxidant properties. Industries such as brewing, natural product research, and pharmaceutical development need it for product stabilization, flavor/aroma studies, and as a precursor for synthesizing novel derivatives. Its stability profile requires careful handling to maintain efficacy and purity for industrial and research applications.

Application

• As a primary bittering and preservative agent in the brewing industry, contributing to beer flavor stability and shelf-life.
• As a reference standard and analytical marker in quality control laboratories for hop product analysis and authentication.
• In phytochemical and natural product research for studying the bioactivity of hop-derived compounds.
• As a starting material or intermediate for the synthesis of specialized chemical derivatives with enhanced properties.
• In antimicrobial formulation research, leveraging its natural inhibitory effects against certain bacteria.
• For flavor and fragrance applications where specific hop resin profiles are required.

Basic Information

Product Name	Lupulone
CAS No.	468-28-0
Molecular Formula	C26H38O4
Molecular Weight	414.58 g/mol
Synonyms	β-Bitter Acid; β-Lupulic Acid; β-Acid; 3,5-Dihydroxy-4,6-bis(3-methyl-2-butenyl)-2-(3-methyl-1-oxobutyl)benzoic Acid; Hop beta Acid; Colupulone; Humulone β-acid; NSC 169854
EINECS	207-411-5

Quality Control

Our Lupulone is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high purity and consistency, with specifications tailored to meet research and industrial grade requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) under an inert atmosphere to minimize oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to Amber Powder or Resin
Identification (IR)	Conforms to Reference Spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.