Description

Diginin CAS NO 467-53-8 is a specialized cardiac glycoside derivative, a compound of significant interest in pharmaceutical research and development. Its core value lies in its structural relationship to other potent cardiotonic agents, making it a crucial reference standard and a key intermediate for synthesizing novel therapeutic molecules. This product is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers focused on cardiovascular drug discovery, analytical method development, and the production of high-purity active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in the production of cardiac glycoside-based drugs.
• Biochemical Research: Serves as a critical tool in pharmacological studies to investigate the structure-activity relationships (SAR) of cardiotonic steroids and their interaction with Na+/K+-ATPase.
• API Intermediate: Acts as a key synthetic building block in the multi-step synthesis of more complex cardiac-active pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for studying the mechanisms of heart failure and developing new therapeutic approaches.
• Analytical Chemistry: Employed in developing and calibrating advanced analytical techniques such as HPLC, LC-MS, and NMR for the detection and quantification of related substances.

Basic Information

Product Name	Diginin
CAS No.	467-53-8
Molecular Formula	C23H32O6
Molecular Weight	404.50 g/mol
Synonyms	Diginigenin; 3β,14-Dihydroxy-5β-card-20(22)-enolide; (3β,5β)-3,14-Dihydroxy-19-oxocard-20(22)-enolide; 14-Hydroxydigitoxigenin; NSC 32917; Card-20(22)-enolide, 3,14-dihydroxy-, (3β,5β)-; Diginigenin
EINECS	Contact for details

Quality Control

Every batch of Diginin (CAS 467-53-8) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure they meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.