Description

3α,14-Dihydroxy-5α-Card-20(22)-Enolide is a high-purity cardenolide derivative, a key structural motif in bioactive natural products. This compound is valued for its role as a critical intermediate in pharmaceutical research and development, particularly in the synthesis of cardiac glycosides and other specialized fine chemicals. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors seeking reliable, high-quality building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: A crucial precursor in the research and synthesis of cardiac glycosides and related therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
• Organic Synthesis: Serves as a sophisticated chiral building block for the total synthesis of complex natural products and novel chemical entities.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing of related compounds.
• Academic & Industrial R&D: Fundamental material for exploring new medicinal chemistry routes and structure-activity relationships (SAR) within the cardenolide class.

Basic Information

Item	Details
Product Name	3α,14-Dihydroxy-5α-Card-20(22)-Enolide
CAS No.	466-08-0
Molecular Formula	C23H34O4
Molecular Weight	374.52 g/mol
Synonyms	3α,14-Dihydroxy-5α-card-20(22)-enolide; 3α,14-Dihydroxy-5α-card-20(22)-enolide; 3α,14-Dihydroxy-5α-cardenolide; 3α,14-Dihydroxy-5α-card-20(22)-enolide; 3α,14-Dihydroxy-5α-card-20(22)-enolide; 3α,14-Dihydroxy-5α-card-20(22)-enolide; 3α,14-Dihydroxy-5α-card-20(22)-enolide; 3α,14-Dihydroxy-5α-card-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3α,14-Dihydroxy-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.