Description

3-Fluoropropan-1-Amine is a versatile fluorinated amine building block of significant importance in modern synthetic chemistry. Its value lies in its ability to introduce fluorine and amine functionalities into target molecules, enabling the fine-tuning of physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds with enhanced biological activity, stability, or performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom improves metabolic stability and membrane permeability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorinated Polymer & Material Science: Incorporated into monomers for synthesizing specialty polymers with unique surface properties, chemical resistance, and durability.
• Bioconjugation & Probe Synthesis: Utilized in the preparation of fluorescent probes, biomarkers, and bioconjugates for diagnostic and research applications.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and reductive amination reactions to construct complex organic frameworks.

Basic Information

Item	Detail
Product Name	3-Fluoropropan-1-Amine
CAS No.	462-41-9
Molecular Formula	C3H8FN
Molecular Weight	77.10 g/mol
Synonyms	3-Fluoropropylamine; 3-Fluoropropanamine; 1-Amino-3-fluoropropane; γ-Fluoropropylamine; 3-Fluoropropan-1-amine; 3-FPA; 3-Fluor-1-propylamin; 3-Fluoropropilamina
EINECS	Contact for details

Quality Control

Our 3-Fluoropropan-1-Amine is manufactured under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for production, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, the container should be kept tightly sealed and allowed to reach room temperature before opening to minimize moisture ingress and loss. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.