Description

3,3,3-Trifluoropropylamine is a versatile organofluorine building block characterized by its reactive primary amine group and trifluoromethyl moiety. This compound matters for its ability to introduce both basicity and the unique physicochemical properties of fluorine into target molecules, such as enhanced metabolic stability, lipophilicity, and bioavailability. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce amine functionality and fluorinated side chains into polymers, enhancing surface properties, chemical resistance, and durability.
• Crosslinking Agent: Acts as a reactive monomer or crosslinker in epoxy resins and other thermosetting polymers.
• Organic Synthesis Reagent: A valuable reagent for introducing the 3,3,3-trifluoropropyl group into complex organic molecules via amidation, reductive amination, or nucleophilic substitution reactions.

Basic Information

Product Name	3,3,3-Trifluoropropylamine
CAS No.	460-39-9
Molecular Formula	C3H6F3N
Molecular Weight	113.08 g/mol
Synonyms	3,3,3-Trifluoropropan-1-amine; 3,3,3-Trifluoro-1-propanamine; 1-Amino-3,3,3-trifluoropropane; 3,3,3-Trifluoropropylamine; 3-(Trifluoromethyl)propylamine; γ,γ,γ-Trifluoropropylamine; 3,3,3-Trifluoropropanamine
EINECS	207-312-3

Quality Control

Our 3,3,3-Trifluoropropylamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global customer base. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizers. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.20 - 1.25
Refractive Index (n20D)	1.340 - 1.360

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.