Description

4-Fluorobenzyl Bromide is a versatile and reactive organobromine compound that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive benzyl bromide group with a fluorine substituent, enabling precise molecular construction for high-value applications. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable, high-purity raw materials for their development and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated benzyl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Cross-Coupling Reactions: Employed in palladium-catalyzed reactions (e.g., Suzuki, Heck) to introduce the 4-fluorobenzyl group into complex molecules.
• Functional Polymer Modification: Used to graft fluorinated aromatic groups onto polymer chains to alter surface properties and chemical resistance.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	4-Fluorobenzyl Bromide
CAS No.	459-46-1
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	α-Bromo-4-fluorotoluene; (4-Fluorophenyl)methyl Bromide; 1-(Bromomethyl)-4-fluorobenzene; p-Fluorobenzyl Bromide; 4-Fluorobenzylbromide; 4-Fluorobenzyl Bromide; 4-Fluoro-α-bromotoluene; 4-Fluorobenzyl Bromide (p-Fluorobenzyl Bromide)
EINECS	207-306-5

Quality Control

Our 4-Fluorobenzyl Bromide is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to quality supports applications requiring GMP-grade intermediates and reliable supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.